The Spanish verb 'enfadar' (to anger) comes from combining the Latin prefix 'in-' meaning 'into, towards' with the Latin word 'fatum' meaning 'fate, destiny'. The noun form 'enfado' (anger) was formed first, and then the verb was created by adding the Spanish infinitive suffix '-ar'. The semantic development from 'fate/destiny' to 'anger' likely came from the idea of being 'pushed into one's fate' or being 'against one's fate', which evolved to express the feeling of being upset or angered.

A common related Spanish word is the noun 'enfado' meaning 'anger' or 'annoyance', which is the base from which the verb 'enfadar' was formed. You might also encounter 'enfadoso' (annoying) and 'enfadado/a' (angry), which are all part of this word family derived from the same Latin roots.

While English 'fate' comes from the same Latin word 'fatum' that gave us 'enfadar', the meanings have diverged significantly. English preserved the original meaning of destiny or predetermined outcome, while the Spanish word developed to express anger or annoyance. The English prefix 'in-' (as in 'inside' or 'into') is also related to the Latin prefix used in 'enfadar'.