desquiciar
unsettle
des-
un-, dis-
+
quicio
hinge
+
-ar
verb suffix
Desquiciar means to unsettle and can be thought of as des-0 (un-0) + quicio1 (hinge1) + -ar2 (verb2), literally meaning 'to unhinge'.
verb
  1. unsettle
    To unsettle or drive someone crazy
    Su comportamiento errático me desquicia. // His erratic behavior unsettles me.
  2. unhinge
    To unhinge or remove from hinges
    Tuvimos que desquiciar la puerta para repararla. // We had to unhinge the door to repair it.