The Mexican Spanish interjection 'chale' comes from an onomatopoeia - specifically the sound 'tch' that people make to express disgust or disapproval. This is similar to how the English 'tsk-tsk' or 'tut-tut' developed as representations of disapproving sounds. In Mexican Spanish, this sound evolved into the more formalized interjection 'chale', which is used to express disagreement, annoyance, or rejection of something.

Since 'chale' developed from a sound rather than from other Spanish words, there aren't any simpler Spanish words that share its etymology. However, it's worth noting that Spanish has other interjections that developed from sounds, such as 'ay' (expressing pain or surprise) and 'uf' (expressing exhaustion or exasperation).

While 'chale' doesn't have any etymologically related English words (since it developed independently from a sound), English speakers might find it helpful to think of similar expressions of disapproval in English like 'tsk-tsk' or 'tut-tut', which also originated as representations of sounds made to express disapproval.