The Spanish word 'cocaína' (cocaine) comes from combining two elements: 'coca' and the suffix '-ina'. The base word 'coca' comes from Quechua/Aymara 'kuka', which refers to the coca plant native to South America. The suffix '-ina' is used in Spanish (and other languages) to form names of chemical substances. When these elements combined, they created 'cocaína', literally meaning 'the chemical substance derived from coca.'

A simpler related Spanish word is 'coca', which refers directly to the coca plant. This is a much more basic word that Spanish learners might encounter when learning about South American culture and history.

The English word 'cocaine' is directly related to Spanish 'cocaína', as both languages borrowed and adapted the word in similar ways. English also uses the word 'coca' when referring to the plant itself. The chemical suffix '-ine' in English serves the same purpose as Spanish '-ina', both being used to name chemical substances.